| Autor: |
Sidiakina TM, Ustiuzhanina SV, Novikova ND, Gorin SE, Esipova VV, Kalakutskiĭ LV |
| Jazyk: |
ruština |
| Zdroj: |
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 1990 Jan; Vol. 35 (1), pp. 11-4. |
| Abstrakt: |
The influence of various preservation conditions of viability and antibiotic activity of Acremonium chrysogenum 281A and 305A strains producing cephalosporin C was studied. Cryogenization of the culture in the form of suspension of the vegetative mycelium in 20 per cent glycerol solution at a rate of 1 degree/min showed to be advantageous over lyophilization and L-drying. Cryogenization under such conditions provided rather high viability of the culture and preservation of its initial antibiotic activity for the period of its storage for at least 1.5 years in liquid nitrogen at a temperature of -196 degrees C. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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