| Autor: |
Martinho AP; Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, UNESP - Univ. Estadual Paulista, Botucatu, State of Sao Paulo, Brazil. aninhavitty@uol.com.br, Franco MM, Ribeiro MG, Perrotti IB, Mangia SH, Megid J, Vulcano LC, Lara GH, Santos AC, Leite CQ, de Carvalho Sanches O, Paes AC |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2013 Mar; Vol. 88 (3), pp. 596-600. Date of Electronic Publication: 2013 Jan 21. |
| DOI: |
10.4269/ajtmh.12-0332 |
| Abstrakt: |
An uncommon disseminated Mycobacterium tuberculosis infection is described in a 12-year-old female dog presenting with fever, dyspnea, cough, weight loss, lymphadenopathy, melena, epistaxis, and emesis. The dog had a history of close contact with its owner, who died of pulmonary tuberculosis. Radiographic examination revealed diffuse radio-opaque images in both lung lobes, diffuse visible masses in abdominal organs, and hilar and mesenteric lymphadenopathy. Bronchial washing samples and feces were negative for acid-fast organisms. Polymerase chain reaction (PCR)-based species identification of bronchial washing samples, feces, and urine revealed M. tuberculosis using PCR-restriction enzyme pattern analysis-PRA. Because of public health concerns, which were worsened by the physical condition of the dog, euthanasia of the animal was recommended. Rough and tough colonies suggestive of M. tuberculosis were observed after microbiological culture of lung, liver, spleen, heart, and lymph node fragments in Löwenstein-Jensen and Stonebrink media. The PRA analysis enabled diagnosis of M. tuberculosis strains isolated from organs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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