The effect of medicaments used in endodontic regeneration on root fracture and microhardness of radicular dentine.

Autor: Yassen GH; Department of Restorative Dentistry, Division of Dental Biomaterials, Indiana University School of Dentistry, Indianapolis, IN 46202, USA. gyassen@iupui.edu, Vail MM, Chu TG, Platt JA
Jazyk: angličtina
Zdroj: International endodontic journal [Int Endod J] 2013 Jul; Vol. 46 (7), pp. 688-95. Date of Electronic Publication: 2013 Jan 21.
DOI: 10.1111/iej.12046
Abstrakt: Aim: To investigate the effect of medicaments used in endodontic regeneration on root fracture resistance and microhardness of radicular dentine.
Methodology: The root canals of mandibular premolars (n = 180) were instrumented and randomized into three treatment groups and an untreated control group. Each treatment group received either triple antibiotic paste (TAP), double antibiotic paste (DAP) or calcium hydroxide paste [Ca(OH)₂] intracanal medicament. Teeth were kept in saline for 1 week, 1 month or 3 months. After each time-point, 15 teeth were randomly selected from each group and two root cylinders were obtained from each tooth. One cylinder was subjected to a fracture resistance test, and the other cylinder was used for a microhardness test. Two-way ANOVA and Tukey's pairwise comparisons were used for statistical analysis.
Results: For the microhardness test, the two-way interaction between group and time was significant (P < 0.001). The intracanal application of TAP and DAP caused significant and continuous decrease in root dentine microhardness after one (P < 0.05) and 3 months (P < 0.001), respectively. The three-month intracanal application of Ca(OH)₂ significantly increased the microhardness of root dentine (P < 0.05). The time factor had a significant effect on fracture resistance (P < 0.001). The three intracanal medicaments caused significant decreases in fracture resistance ranging between 19% and 30% after 3-month application compared to 1-week application.
Conclusion: In this laboratory study, the 3-month application of triple antibiotic paste, double antibiotic paste or calcium hydroxide paste medicaments significantly reduced the root fracture resistance of extracted teeth compared to a 1-week application.
(© 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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