Retinal angiomatous proliferation occurring after radiotherapy.

Autor: De Salvo G; Southampton Eye Unit, University Hospital Southampton, Southampton, UK., Hannan SR, James N, Lotery AJ
Jazyk: angličtina
Zdroj: Eye (London, England) [Eye (Lond)] 2013 Mar; Vol. 27 (3), pp. 447-9. Date of Electronic Publication: 2013 Jan 04.
DOI: 10.1038/eye.2012.274
Abstrakt: Purpose: To describe two cases of retinal angiomatous proliferation (RAP)-like lesion following radiation therapy for primary tumor.
Patients and Methods: Retrospective evaluation of two patients with previous irradiation treatment for a pleomorphic adenoma of the lacrimal gland and a vocal cord carcinoma, respectively. Visual acuity (VA), fluorescein angiography and optical coherence tomography were performed and demonstrated a RAP-like lesion in both cases. Treatment with intravitreal injections of Ranibizumab was performed with a follow-up of 19 and 10 months, respectively.
Results: Both the patients had a positive response to the treatment with improvement in VA and reduction of intraretinal fluid.
Conclusion: RAP-like lesions can develop following radiation treatment for a primary tumor. In patients presenting with idiopathic RAP, a history of prior radiotherapy should be considered.
Databáze: MEDLINE