| Autor: |
Xu M; Dept of Laboratories, Seattle Children's Hospital, Seattle, WA 98105, USA. min.xu@seattlechildrens.org, Qin X, Astion ML, Rutledge JC, Simpson J, Jerome KR, Englund JA, Zerr DM, Migita RT, Rich S, Childs JC, Cent A, Del Beccaro MA |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of clinical pathology [Am J Clin Pathol] 2013 Jan; Vol. 139 (1), pp. 118-23. |
| DOI: |
10.1309/AJCPH7X3NLYZPHBW |
| Abstrakt: |
The FilmArray respiratory virus panel detects 15 viral agents in respiratory specimens using polymerase chain reaction. We performed FilmArray respiratory viral testing in a core laboratory at a regional children's hospital that provides service 24 hours a day 7 days a week. The average and median turnaround time were 1.6 and 1.4 hours, respectively, in contrast to 7 and 6.5 hours documented 1 year previously at an on-site reference laboratory using a direct fluorescence assay (DFA) that detected 8 viral agents. During the study period, rhinovirus was detected in 20% and coronavirus in 6% of samples using FilmArray; these viruses would not have been detected with DFA. We followed 97 patients with influenza A or influenza B who received care at the emergency department (ED). Overall, 79 patients (81%) were given oseltamivir in a timely manner defined as receiving the drug in the ED, a prescription in the ED, or a prescription within 3 hours of ED discharge. Our results demonstrate that molecular technology can be successfully deployed in a nonspecialty, high-volume, multidisciplinary core laboratory. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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