| Autor: |
Rigoli JW; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA., Weatherly CD, Vo BT, Neale S, Meis AR, Schomaker JM |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2013 Jan 18; Vol. 15 (2), pp. 290-3. Date of Electronic Publication: 2012 Dec 24. |
| DOI: |
10.1021/ol303167n |
| Abstrakt: |
Allene aziridination generates useful bicyclic methylene aziridine scaffolds that can be flexibly transformed into a range of stereochemically complex and densely functionalized amine-containing stereotriads. The scope of this chemistry has been limited by the poor chemoselectivity that often results when typical dinuclear Rh(II) catalysts are employed with homoallenic carbamates. Herein, Ag(I) catalysts that significantly improve the scope and yield of bicyclic methylene aziridines that can be prepared via allene aziridination are described. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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