| Autor: |
Neely JM; Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States., Rovis T |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Chemical Society [J Am Chem Soc] 2013 Jan 09; Vol. 135 (1), pp. 66-9. Date of Electronic Publication: 2012 Dec 18. |
| DOI: |
10.1021/ja3104389 |
| Abstrakt: |
α,β-Unsaturated O-pivaloyl oximes are coupled to alkenes by Rh(III) catalysis to afford substituted pyridines. The reaction with activated alkenes is exceptionally regioselective and high-yielding. Mechanistic studies suggest that heterocycle formation proceeds via reversible C-H activation, alkene insertion, and a C-N bond formation/N-O bond cleavage process. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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