Daily and Weekly Iron Supplementations are Effective in Increasing Hemoglobin and Reducing Anemia in Infants.

Autor:	Nogueira Arcanjo FP; Federal University of Ceara, Sobral Unit, 62042-280 Sobral, Ceara, Brazil. franciscoplacidoarcanjo@gmail.com, Santos PR, Costa Arcanjo CP, Meira Magalhães SM, Madeiro Leite AJ
Jazyk:	angličtina
Zdroj:	Journal of tropical pediatrics [J Trop Pediatr] 2013 Jun; Vol. 59 (3), pp. 175-9. Date of Electronic Publication: 2012 Dec 13.
DOI:	10.1093/tropej/fms071
Abstrakt:	Objective: The objective of this study was to evaluate the effect of daily and weekly iron supplementation compared with control on hemoglobin values and anemia prevalence in infants. Methods: In this cluster-randomized study, we evaluated infants aged 12-24 months (n = 210) from three public daycare centers, during 4 months. Intervention-group A was allocated 25 mg elemental iron once weekly; intervention-group B received 12.5 mg elemental iron once daily; control-group C received 0.5 ml of a natural color additive. Hemoglobin was assessed before and after intervention. Results: Baseline mean hemoglobin was 8.81 ± 0.89 g/dl (group A), 9.70 ± 1.56 g/dl (group B) and 10.96 ± 0.92 g/dl (group C); after intervention, mean hemoglobin was 10.03 ± 0.78 g/dl (p < 0.0001), 10.65 ± 0.97 g/dl (p < 0.0001) and 11.30 ± 0.80 g/dl (p = 0.0034) for groups A, B and C, respectively. Anemia prevalence was as follows: group A, 100% at baseline and 83.3% at end of study, p = 0.0001; group, B 75.0% and 41.7%, p = 0.0002; group C, 50.0% and 37.5%, p = 0.182. Conclusions: Weekly and daily iron supplementation were effective in increasing hemoglobin levels and reducing anemia in infants.
Databáze:	MEDLINE
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