An unusual suspect causing behavioural problems and pituitary failure in a child.

Autor: Heathcote AC; Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK., Wormald JC, Stocks R
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2012 Dec 14; Vol. 2012. Date of Electronic Publication: 2012 Dec 14.
DOI: 10.1136/bcr-2012-006870
Abstrakt: A 9-year-old boy presented with feeding and behavioural problems and was diagnosed with Autistic Spectrum Disorder and Attention Deficit Hyperactivity Disorder. By age 11 he was becoming increasingly disinhibited and was refusing almost all oral food intake. Believing the cause to be psychogenic, he was placed in an inpatient eating disorder facility. After 3 days of continuous vomiting and minimal intake, he was admitted back to hospital for further investigations. A hypovolaemic hypernatraemia prompted an MRI brain scan, revealing several tumour masses with suprasellar and pituitary involvement. Histological investigation revealed primary, non-malignant germ-cell tumours. The tumours were treated with craniopharyngeal radiotherapy and permanent pituitary hormone replacement.
Databáze: MEDLINE