Unilateral eyelid mass as an unusual presentation of ocular adnexal IgG4-related inflammation.
| Autor: | da Fonseca FL; Department of Ophthalmology, University of São Paulo School of Medicine Hospital, São Paulo, Brazil., Ramos Rde I, de Lima PP, Nogueira AB, Matayoshi S |
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| Jazyk: | angličtina |
| Zdroj: | Cornea [Cornea] 2013 Apr; Vol. 32 (4), pp. 517-9. |
| DOI: | 10.1097/ICO.0b013e3182775de4 |
| Abstrakt: | Purpose: IgG4-related sclerosing disease is a new clinicopathologic systemic entity, which can involve ocular adnexal structures, such as lacrimal glands and orbital tissues. However, this entity seems to display a more diffuse, frequently bilateral, pattern in such cases. Conjunctival involvement has not been reported in this disease. Methods: We report the case of a 67-year-old woman with left upper palpebral mass for 5 months. A biopsy was performed, and the patient underwent systemic evaluation for IgG4-related disease. Results: The clinicopathologic study revealed intense lymphoplasmacytic and sclerosing inflammation, with IgG4-positive plasma cells and an IgG4:IgG ratio >40%. The conjunctiva was also involved, which was different from previous studies. The only abnormality was hyperglycemia at 180 mg/dL (reference range, 70-99 mg/dL) and a raised glycosylated hemoglobin at 7.8%. Serum IgG and IgG4 levels were normal. Conclusions: Our case presented an unusual framework of ocular adnexal IgG4-related inflammation, with a more benign and restricted palpebral manifestation involving the conjunctiva. |
| Databáze: | MEDLINE |
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