[Peculiarities of age changes of NF200(+)-neurons in the sensory ganglia of different segmental levels after chemical deafferentation].

Autor: Porseva VV, Shilkin VV, Korzina MB, Smirnova VP, Masliukov PM
Jazyk: ruština
Zdroj: Morfologiia (Saint Petersburg, Russia) [Morfologiia] 2012; Vol. 142 (4), pp. 37-42.
Abstrakt: Morphological features of the neurons containing neurofilaments with molecular mass of 200 kD (NF200+), were studied in the sensory ganglia of thoracic and lumbar spinal nerves in rats (n = 80) during the first year of their life. Capsaicin treatment (150 mg/kg) of the newborn animals resulted in the change of age dynamics of NF200+ neurons. This was reflected by a reduction of NF200+ neuron numbers and their cross-sectional areas in both ganglia. Segmental differences included greater reduction of NF200+ neuron number in the sensory ganglion of lumbar spinal nerve in both early and late developmental periods.
Databáze: MEDLINE