Comparison of microalbuminuria with hs-CRP and low density lipoprotein levels in nondiabetic, nonhypertensive myocardial infarction patients.
| Autor: | Goud BK; Department of Biochemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, U.A.E., Nayal B, Devi OS, Devaki RN, Avinash SS, Satisha TG, Raghuveer CV |
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| Jazyk: | angličtina |
| Zdroj: | Journal of cardiovascular disease research [J Cardiovasc Dis Res] 2012 Oct; Vol. 3 (4), pp. 287-9. |
| DOI: | 10.4103/0975-3583.102702 |
| Abstrakt: | Introduction: Microalbuminuria (MA), defined as urine albumin to urine creatinine ratio (UACR) of 30 to 300 mg/G of creatinine, is an established risk factor for cardiovascular morbidity and mortality and for end-stage renal disease in individuals with an adverse cardiovascular risk profile such as those with hypertension or/and diabetes mellitus. Materials and Methods: Thirty five patients were included in the study and equal number of age- and sex-matched controls were also included. 2 ml of venous blood was collected for hs-CRP determination and early morning mid stream urine sample was collected under strict aseptic precautions. The lipid profile was estimated in cobas autoanalyzer. Results: There was significant increase in levels of Low density lipoprotein (LDL) cholesterol, microalbumin, and hs-CRP (P< 0.001) in patients with myocardial infarction compared to healthy controls. Conclusion: Therefore, MA and hsCRP evaluation may have potential role in improving cardiovascular risk prediction, when used along with traditional lipid profiles. |
| Databáze: | MEDLINE |
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