| Autor: |
Bobb V; New York City Children's Center, New York State Office of Mental Health, Brooklyn, NY, USA. vanessa.bobb@omh.ny.gov, Weinberg M, Gabel S, Kranzler H, Olfson M |
| Jazyk: |
angličtina |
| Zdroj: |
The Psychiatric quarterly [Psychiatr Q] 2013 Sep; Vol. 84 (3), pp. 343-9. |
| DOI: |
10.1007/s11126-012-9250-2 |
| Abstrakt: |
We assessed the predictors of clozapine initiation among youth 18 years and younger within a state psychiatric hospital. Administrative data (n = 358) were evaluated of inpatients from a long-term state child and adolescent psychiatric hospital. We investigated 25 background and clinical patient characteristics to determine which factors predicted clozapine initiation following the first 21 days of hospital admission. A Cox proportional model was used to evaluate factors that independently predicted the hazard rate of clozapine initiation. Emergency medication administration during the first 3 weeks of admission, which was more common among the clozapine (84.9 %) than control (61.7 %) patients (p < 0.001), was associated with a significantly increased probability of clozapine initiation (Hazard Ratio = 1.9, 95 % Confidence Interval = 1.2-3.1). Use of a mood stabilizer during the first 3 weeks of the inpatient was non-significantly related to an increased probability of clozapine initiation (Hazard Ratio = 1.7, 95 % Confidence Interval = 1.0-2.9). In this setting, emergency medication use predicts clozapine initiation suggesting that it may be used to treat patients with aggressive behavior. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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