The Hmong Diaspora: preserved South-East Asian genetic ancestry in French Guianese Asians.
| Autor: | Brucato N; UMR 5288 CNRS, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Paul-Sabatier Toulouse III, Toulouse, France., Mazières S, Guitard E, Giscard PH, Bois E, Larrouy G, Dugoujon JM |
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| Jazyk: | angličtina |
| Zdroj: | Comptes rendus biologies [C R Biol] 2012 Oct-Nov; Vol. 335 (10-11), pp. 698-707. Date of Electronic Publication: 2012 Nov 07. |
| DOI: | 10.1016/j.crvi.2012.10.003 |
| Abstrakt: | The Hmong Diaspora is one of the widest modern human migrations. Mainly localised in South-East Asia, the United States of America, and metropolitan France, a small community has also settled the Amazonian forest of French Guiana. We have biologically analysed 62 individuals of this unique Guianese population through three complementary genetic markers: mitochondrial DNA (HVS-I/II and coding region SNPs), Y-chromosome (SNPs and STRs), and the Gm allotypic system. All genetic systems showed a high conservation of the Asian gene pool (Asian ancestry: mtDNA=100.0%; NRY=99.1%; Gm=96.6%), without a trace of founder effect. When compared across various Asian populations, the highest correlations were observed with Hmong-Mien groups still living in South-East Asia (Fst<0.05; P-value<0.05). Despite a long history punctuated by exodus, the French Guianese Hmong have maintained their original genetic diversity. (Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.) |
| Databáze: | MEDLINE |
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