Verification of natural infection of peridomestic rodents by PCV2 on commercial swine farms.

Autor: Pinheiro AL; Laboratório de Infectologia Molecular Animal (LIMA), Departamento de Veterinária, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs s/n, Campus Universitário, 36570-000 Viçosa, Minas Gerais, Brazil., Bulos LH, Onofre TS, de Paula Gabardo M, de Carvalho OV, Fausto MC, Guedes RM, de Almeida MR, Silva Júnior A
Jazyk: angličtina
Zdroj: Research in veterinary science [Res Vet Sci] 2013 Jun; Vol. 94 (3), pp. 764-8. Date of Electronic Publication: 2012 Nov 09.
DOI: 10.1016/j.rvsc.2012.10.006
Abstrakt: The porcine circovirus-2 (PCV2) is the main agent responsible for porcine circovirus associated diseases (PCVAD). Few studies have been done regarding PCV2 infection in other species. The purpose of this study was to investigate the occurrence of PCV2 infection in the peridomestic rodent species Mus musculus and Rattus rattus on commercial pig farms in Brazil. Immunohistochemistry assay demonstrated PCV2 in the spleen, lung and kidney. Viral DNA was detected in tissues by nested PCR assay. Partial sequences of PCV2 genomes detected in the rodents had strong identity with gene sequences of PCV2 isolates from pigs. These results show that the studied peridomestic rodent species can be naturally infected by PCV2. However, further studies are needed to confirm PCV2 transmission from rodents to pigs.
(Copyright © 2012 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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