Anti-PreS2 antibody assay for evaluating immune responses among recipients of recombinant hepatitis B PreS2 + S vaccine.

Autor: Hurni WM; Virus and Cell Biology Research, Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania., Roehm RR, Miller WJ
Jazyk: angličtina
Zdroj: Journal of medical virology [J Med Virol] 1990 Feb; Vol. 30 (2), pp. 146-50.
DOI: 10.1002/jmv.1890300213
Abstrakt: A competitive radioimmunoassay was developed for measuring hepatitis B virus (HBV) anti-PreS2 antibody. The assay has been demonstrated to be highly specific for anti-PreS2 antibody and not subject to interference by other antibodies to HBV-specific antigens. This assay was used to evaluate anti-PreS2 antibody responses in a hepatitis B PreS2 + S vaccine human clinical trial in healthy adults.
Databáze: MEDLINE