[Three patterns of trypanosomatid cryptogene structural organization].

Autor: Gerasimov ES, Efimova NS, Kolesnikov AA
Jazyk: ruština
Zdroj: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2012 Jul-Aug; Vol. 46 (4), pp. 612-21.
Abstrakt: We sequenced a number of cryptogenes from previously unstudied species of homoxenous trypanosomatids belonging to the different phylogenetic groups and found new examples of editing domain length reduction for A6 and COIII. The comparative analyzes of sequences allows to divide the cryptogenes in three groups (patterns) according to the degree of primary structure conservation and editing domain length variation. We discuss the possible factors which influence the cryptogene's structure and evolutionary behavior. Also we demonstrate alternative editing of rps12 transcript in Wallaceina sp. Wsd.
Databáze: MEDLINE