Increased β-endorphin level in blood plasma as an indicator of positive response to depression treatment.

Autor: Kubryak OV; PK Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia. o.kubryak@nphys.ru, Umriukhin AE, Emeljanova IN, Antipova OS, Guseva AL, Pertsov SS, Sudakov SK
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Sep; Vol. 153 (5), pp. 758-60.
DOI: 10.1007/s10517-012-1819-0
Abstrakt: Preliminary data indicate that increased blood plasma level of β-endorphin in patients with nonpsychotic unipolar depression after 2 weeks of treatment correlates with the positive response to therapy. This parameter can be regarded as an objective indicator of potential improvements. Further studies aimed at determining the value of blood β-endorphin levels in patients with mood disorders for the diagnostics and estimating the therapeutic success in this disease are required.
Databáze: MEDLINE