Mycobacterium africanum, an emerging disease in high-income countries?
| Autor: | Isea-Peña MC; Department of Clinical Microbiology, Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Madrid, Spain., Brezmes-Valdivieso MF, González-Velasco MC, Lezcano-Carrera MA, López-Urrutia-Lorente L, Martín-Casabona N, Monforte-Cirac ML, Palacios JJ, Penedo-Pallares A, Ramirez-Rosales A, Sánchez-Silos R, Tórtola-Fernández T, Viñuelas-Bayón J, Vitoria-Agreda A, Esteban J |
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| Jazyk: | angličtina |
| Zdroj: | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2012 Oct; Vol. 16 (10), pp. 1400-4. |
| DOI: | 10.5588/ijtld.12.0142 |
| Abstrakt: | Background: Mycobacterium africanum is a cause of tuberculosis (TB) that has mainly been described in Africa, but immigration and travel patterns have contributed to the spread of the disease to other countries. Methods: We retrospectively reviewed TB cases due to M. africanum during 2000-2010 in seven Spanish hospitals. Selected clinical charts were reviewed using a predefined protocol that included demographical, clinical and microbiological data and outcome. Results: Although 57 cases were diagnosed, only 36 clinical charts were available for review: 82.8% were men and the mean age was 31.6 years (range 12-81). Forty-four cases were from Africa, 1 from the Philippines, 1 from India, and 4 from Spain, while the country of origin was unknown in 7 cases. The most frequent site of infection was the lung (58.3%). Four cases (6.9%) were resistant to at least one first-line anti-tuberculosis drug. Conclusions: Disease due to M. africanum in industrialised countries is mainly associated with immigration from endemic areas, although some cases also occur among native-born populations. |
| Databáze: | MEDLINE |
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