| Autor: |
Schaumburg F; Medical Research Unit, Albert Schweitzer Hospital Lambaréné, Lambaréné, Gabon. frieder.schaumburg@ukmuenster.de, Biallas B, Alabi AS, Grobusch MP, Feugap EN, Lell B, Mellmann A, Peters G, Kremsner PG, Becker K, Adegnika AA |
| Jazyk: |
angličtina |
| Zdroj: |
Epidemiology and infection [Epidemiol Infect] 2013 Aug; Vol. 141 (8), pp. 1717-20. Date of Electronic Publication: 2012 Oct 10. |
| DOI: |
10.1017/S0950268812002270 |
| Abstrakt: |
Children with sickle cell anaemia (SCA) might carry hospital-associated bacterial lineages due to frequent hospital stays and antibiotic treatments. In this study we compared Staphylococcus aureus from SCA patients (n=73) and healthy children (n=143) in a cross-sectional study in Gabon. S. aureus carriage did not differ between children with SCA (n=34, 46∙6%) and controls matched for age, residence and sex (n=67, 46∙9%). Both groups shared similar S. aureus genotypes. This finding points towards a transmission of S. aureus between both groups in the community. We conclude that resistance rates from population-based studies with healthy participants could therefore also be used to guide treatment and prophylaxis of endogenous infections in children with SCA despite a different selection pressure. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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