Paget's Disease of the Breast in a Patient with Amyopathic Dermatomyositis.

Autor: Yasar S; Department of Dermatology, Haydarpaşa Numune Teaching and Research Hospital, 34668 Istanbul, Turkey., Gurleyik G, Sabuncuoglu Y, Aktekin A, Yasar B, Serdar ZA
Jazyk: angličtina
Zdroj: Case reports in medicine [Case Rep Med] 2012; Vol. 2012, pp. 515691. Date of Electronic Publication: 2012 Sep 19.
DOI: 10.1155/2012/515691
Abstrakt: Amyopathic dermatomyositis (AD) can be a part of paraneoplastic syndrome of an underlying malignancy. Paget's disease is a rare form of breast cancer. We present a very rare case of Paget's disease associated with AD. Paget's disease has been diagnosed in a patient with AD who is under surveillance of dermatology department. The patient has undergone central lumpectomy with removal of the nipple-areola complex and sentinel lymph node biopsy. Surgical margins after lumpectomy and sentinel node biopsy were negative. The whole breast irradiation was performed after surgery. The patient receives medical treatment for AD of which lesions regressed in 1 year during the follow-up period. This is a very rare case of Paget's disease diagnosed in a patient with AD. Female patients with dermatomyositis have been absolutely recommended to undergo screening for breast and gynaecological malignancies. AD may be an early finding of primary or recurrent malignancy of the breast.
Databáze: MEDLINE