Rosai-Dorfman disease with spontaneous resolution: case report of a child.

Autor: Lima FB; Universidade Federal do Ceará - UFC, Fortaleza, CE, Brazil., Barcelos PS, Constâncio AP, Nogueira CD, Melo-Filho AA
Jazyk: angličtina
Zdroj: Revista brasileira de hematologia e hemoterapia [Rev Bras Hematol Hemoter] 2011; Vol. 33 (4), pp. 312-4.
DOI: 10.5581/1516-8484.20110083
Abstrakt: Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.
Databáze: MEDLINE