Autor: |
de Mascena Diniz Maia PF; Federal University of Vale do São Francisco, Petrolina-PE, Brazil., da Silva TM, Angelo HD, e Silva LW, Gondim Martins DB, de Mascena Diniz Maia M, de Lima Filho JL |
Jazyk: |
angličtina |
Zdroj: |
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2013 Feb; Vol. 26 (3), pp. 316-7. Date of Electronic Publication: 2012 Oct 18. |
DOI: |
10.3109/14767058.2012.733769 |
Abstrakt: |
Insulin-like growth factor 2 (IGF2) gene has an important role in fetal growth. It was investigated association of the IGF2/ApaI polymorphism with low birth weight and normal birth weight (as control) in children attended in Hospital Dom Malan Petrolina, PE-Brazil. The genotype frequencies did not differ statistically between low birth weight (AA = 16.22%, AG = 43.24%, GG = 40.54%) and control (AA = 20% AG = 35%, GG= 45% groups) and the allele frequencies were not significantly different (p > 0.05).The observed genotype frequencies in both groups did not deviate significantly from Hardy-Weinberg equilibrium. Then, no significant correlation was found for this polymorphism in the population studied. |
Databáze: |
MEDLINE |
Externí odkaz: |
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