Efficacy of intradermal radiofrequency combined with autologous platelet-rich plasma in striae distensae: a pilot study.

Autor: Kim IS; Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea., Park KY, Kim BJ, Kim MN, Kim CW, Kim SE
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2012 Oct; Vol. 51 (10), pp. 1253-8.
DOI: 10.1111/j.1365-4632.2012.05530.x
Abstrakt: Background: Different types of laser have recently been reported as effective tools of treatment in striae distensae. Although fractional photothermolysis is effective for striae distensae, post-inflammatory hyperpigmentation is a major concern and common complication. There are no reports of the effects of using an intradermal radiofrequency (RF) device in striae distensae. Autologous platelet-rich plasma (PRP) is an effective treatment known for its wound-healing effects.
Methods: Nineteen Asian female patients with striae distensae were enrolled in this study. Three sessions of intradermal RF (1134-kHz frequency, 12-W power, 26-G electrode size) combined with autologous PRP were performed in each patient at intervals of four weeks. Patients were evaluated subjectively by the investigators and by themselves.
Results: Evaluation of clinical results at four weeks after treatment showed that only one (5.3%) of the 19 patients achieved excellent improvement, whereas seven (36.8%) demonstrated marked improvement, six (31.6%) showed moderate improvement, and five (26.3%) showed mild improvement. None of the patients showed worsening of striae distensae. A total of 63.2% of patients reported they were "satisfied" or "very satisfied" with the degree of overall improvement.
Conclusions:   Intradermal RF combined with autologous PRP appears to be an effective treatment for striae distensae.
(© 2012 The International Society of Dermatology.)
Databáze: MEDLINE