| Autor: |
Ranta K; Department of Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland., Nieminen K, Ekholm FS, Poláková M, Roslund MU, Saloranta T, Leino R, Savolainen J |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2012 Nov; Vol. 19 (11), pp. 1889-93. Date of Electronic Publication: 2012 Sep 19. |
| DOI: |
10.1128/CVI.00298-12 |
| Abstrakt: |
Immunostimulatory properties of synthetic structures mimicking the β-(1→2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(α-D-mannopyranosyloxy)butane induced TNF and some molecules induced low levels of gamma interferon (IFN-γ) in human peripheral blood mononuclear cells (PBMC). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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