| Autor: |
Takeda A; Department of Anesthesiology, Tokyo Medical University, Tokyo 160-8402., Kawamura M, Hamaya I, Kitamura H, Muto R, Mitono H |
| Jazyk: |
japonština |
| Zdroj: |
Masui. The Japanese journal of anesthesiology [Masui] 2012 Aug; Vol. 61 (8), pp. 855-8. |
| Abstrakt: |
Neuromuscular blocking drugs (NMBDs) can predispose patients with myasthenia gravis to postoperative paralysis and respiratory complications. We had a 12-year-old female patient undergoing thoracoscopic thymectomy. She had suffered from MGFA class IIa (mild systemic) myasthenia gravis for 4 months. Anesthesia was induced with 3 mg x kg(-1) of thiopental and 0.2 mg x kg(-1) of rocuronium, which was given incrementally to achieve 100% blockade. Anesthesia was maintained with oxygen, air, 2% sevoflurane and 0.2 microg x kg(-1) x min(-1) of remifentanil. 0.05 mg x kg(-1) of rocuronium was added when the TOF ratio recovered to 20%. Towards the end of the surgery, remifentanil was withdrawn and 4 microg x kg(-1) of fentanyl was given. Intercostal nerve block with 0.2% ropivacaine was performed to relieve postoperative pain. TOF ratio was 32% at the end, when we gave 2 mg x kg(-1) of sugammadex to get 100% reversal of neuromuscular blockade in 120 seconds. There was no residual paralysis and respiratory complications postoperatively. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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