| Autor: |
Van Den Heuvel RL; Environmental Risk and Health Unit-Toxicology, Flemish Institute for Technological Research (VITO N.V.), Centre for Advanced R&D on Alternative Methods (CARDAM), Boeretang 200, 2400, Mol, Belgium, rosette.vandenheuvel@vito.be., Lambrechts N, Verstraelen S, Nelissen IC, Schoeters GE |
| Jazyk: |
angličtina |
| Zdroj: |
Experientia supplementum (2012) [Exp Suppl] 2012; Vol. 101, pp. 289-314. |
| DOI: |
10.1007/978-3-7643-8340-4_10 |
| Abstrakt: |
Chemical sensitization remains an important environmental and occupational health issue. A wide range of substances have been shown to possess the ability to induce skin sensitization or respiratory sensitization. As a consequence, there is a need to have appropriate methods to identify sensitizing agents. Although a considerable investment has been made in exploring opportunities to develop methods for hazard identification and characterization, there are, as yet, no validated nonanimal methods available. A state of the art of the different in vitro approaches to identify contact and respiratory capacity of chemicals is covered in this chapter. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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