Lymphoma of the mediastinum and neck: evaluation with Ga-67 imaging and CT correlation.

Autor: Drossman SR; Department of Radiology, Schneider Children's Hospital, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, NY 11042., Schiff RG, Kronfeld GD, McNamara J, Leonidas JC
Jazyk: angličtina
Zdroj: Radiology [Radiology] 1990 Jan; Vol. 174 (1), pp. 171-5.
DOI: 10.1148/radiology.174.1.2294545
Abstrakt: The role of gallium-67 in the differentiation between active disease and fibrotic changes in patients with childhood lymphoma involving the mediastinum and neck was evaluated prospectively. Ga-67 imaging and computed tomography (CT) were correlated with clinical findings at the time of initial presentation and follow-up in 19 patients. Both modalities enabled detection of active disease on all occasions, but CT results were false-positive for residual disease in 10 patients (53%), whereas Ga-67 imaging results were false-positive in only one patient (5%). Neither modality, however, proved accurate in patients with rebound thymic hyperplasia. Ga-67 imaging is a useful tool for assessing response to therapy in children with lymphoma of the mediastinum and neck.
Databáze: MEDLINE