Beyond growth: novel functions for bacterial cell wall hydrolases.
| Autor: | Wyckoff TJ; Division of Science and Mathematics, University of Minnesota, Morris, MN, USA., Taylor JA, Salama NR |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Trends in microbiology [Trends Microbiol] 2012 Nov; Vol. 20 (11), pp. 540-7. Date of Electronic Publication: 2012 Sep 01. |
| DOI: | 10.1016/j.tim.2012.08.003 |
| Abstrakt: | The peptidoglycan cell wall maintains turgor pressure and cell shape of most bacteria. Cell wall hydrolases are essential, together with synthases, for growth and daughter cell separation. Recent work in diverse organisms has uncovered new cell wall hydrolases that act autonomously or on neighboring cells to modulate invasion of prey cells, cell shape, innate immune detection, intercellular communication, and competitor lysis. The hydrolases involved in these processes catalyze the cleavage of bonds throughout the sugar and peptide moities of peptidoglycan. Phenotypes associated with these diverse hydrolases reveal new functions of the bacterial cell wall beyond growth and division. (Copyright © 2012 Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|
Full Text from ScienceDirect