Pneumocystis jirovecii pneumonia prophylaxis during temozolomide treatment for high-grade gliomas.
| Autor: | De Vos FY; Department of Medical Oncology, University Medical Center Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands. f.devos@umcutrecht.nl, Gijtenbeek JM, Bleeker-Rovers CP, van Herpen CM |
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| Jazyk: | angličtina |
| Zdroj: | Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2013 Mar; Vol. 85 (3), pp. 373-82. Date of Electronic Publication: 2012 Aug 25. |
| DOI: | 10.1016/j.critrevonc.2012.08.002 |
| Abstrakt: | High-grade glioma patients receiving concomitant chemoradiotherapy with temozolomide 75mg/m(2) during six to seven weeks or dose-dense temozolomide regimens especially in combination with chronic use of corticosteroids have a high risk for developing Pneumocystis jirovecii pneumonia. In this review, we define risk groups and propose a guideline for prophylaxis using risk stratification. (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
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