A new prenylated aurone from Artocarpus altilis.

Autor: Huong TT; School of Chemical Engineering, Hanoi University of Science and Technology (HUST), Hanoi, Vietnam., Cuong NX, Tram le H, Quang TT, Duong le V, Nam NH, Dat NT, Huong PT, Diep CN, Kiem PV, Minh CV
Jazyk: angličtina
Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2012; Vol. 14 (9), pp. 923-8. Date of Electronic Publication: 2012 Aug 28.
DOI: 10.1080/10286020.2012.702758
Abstrakt: Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated flavanones (4-6), and three triterpenes (7-9). The structure of 1 was elucidated as 6-hydroxy-2-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-ylmethylene]-3(2H)-benzofuranone by spectroscopic methods including 1D and 2D NMR spectra and FT-ICR-MS. Compound 1 showed moderate nitric oxide radical scavenging activity, whereas 2 and 3 had moderate 2,2-diphenyl-1-picrylhydrazyl radical scavenging effect, compared with the positive control (+)-catechin.
Databáze: MEDLINE
Nepřihlášeným uživatelům se plný text nezobrazuje