Effect of graded doses of Caesalpinia bonducella seed extract on ovary and uterus in albino rats.

Autor: Salunke KR; Karnatak University, Karnataka, India., Ahmed RN, Marigoudar SR
Jazyk: angličtina
Zdroj: Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2011 Jun 17; Vol. 22 (1-2), pp. 49-53. Date of Electronic Publication: 2011 Jun 17.
DOI: 10.1515/jbcpp.2011.006
Abstrakt: Histological changes observed under light microscope illustrate follicular degeneration in ovary, vacuolation and mild disorganization of uterus on treatment with graded doses of alcohol seed extract of Caesalpinia bonducella. There was a significant decrease (p≤0.05) in duration of estrous cycle and mean ovarian weight. However, there were no uniform variations in mean uterine weight, serum estradiol and progesterone level. The results suggest that alcohol seed extract of C. bonducella has antiestrogenic property, possibly acting via inhibition of estrogen secretion.
Databáze: MEDLINE