| Autor: |
Leonardi A; Regional Centre for the Diagnosis and the Treatment of Inflammatory Eye Diseases, University of Padova, Italy., Fregona IA, Gismondi M, Daniotti E, Carniel G, Secchi AG |
| Jazyk: |
angličtina |
| Zdroj: |
Eye (London, England) [Eye (Lond)] 1990; Vol. 4 ( Pt 5), pp. 760-4. |
| DOI: |
10.1038/eye.1990.109 |
| Abstrakt: |
In order to assess the potential usefulness of CPT as a diagnostic tool for ocular allergy, the correlation between skin/RAST tests and CPT was determined in 144 patients affected by allergic 'hay fever' type conjunctivitis. The results showed that an agreement between skin/RAST tests and CPT occurred in 71% of the cases (130/183). Of the 29% uncorrelated cases, 23% (43/183) were positive for at least one specific antigen by skin/RAST tests but not by CPT, while 6% (10/183) were positive for at least one specific antigen by CPT, but not by skin/RAST tests. CPT dramatically increased the histamine levels in tears (p less than 0.001). These findings show that (1) systemic tests can be misleading in that they may suggest a specific sensitisation which, in fact, does not involve the conjunctiva (systemic test positive/CPT negative); (2) CPT can identify local conjunctival sensitisation in the absence of a systemic sensitisation (systemic test negative/CPT positive); (3) CPT can demonstrate that allergic 'hay fever' type conjunctivitis may be related to allergens different from those responsible for a systemic sensitisation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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