Autor: |
van der Kooi-Pol MM; Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Reilman E, Sibbald MJ, Veenstra-Kyuchukova YK, Kouwen TR, Buist G, van Dijl JM |
Jazyk: |
angličtina |
Zdroj: |
Applied and environmental microbiology [Appl Environ Microbiol] 2012 Oct; Vol. 78 (19), pp. 7124-7. Date of Electronic Publication: 2012 Jul 20. |
DOI: |
10.1128/AEM.01565-12 |
Abstrakt: |
Staphylococcus aureus is an important Gram-positive bacterial pathogen producing many secreted and cell surface-localized virulence factors. Here we report that the staphylococcal thiol-disulfide oxidoreductase DsbA is essential for stable biogenesis of the ComGC pseudopilin. The signal peptidase ComC is indispensable for ComGC maturation and optimal cell surface exposure. |
Databáze: |
MEDLINE |
Externí odkaz: |
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