Change in platelet monoamine oxidase activity in the acutest period of ischemic stroke is associated with the degree of neurological recovery.

Autor: Uzbekov MG; Moscow Institute of Psychiatry, Federal Agency for Health Care and Social Development, Russian State Medical University, Moscow, Russia. uzbekovmg@mtunet.ru, Alferova VV, Misionzhnik EY, Gekht AB
Jazyk: English; Russian
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2011 Dec; Vol. 152 (2), pp. 195-7.
DOI: 10.1007/s10517-011-1486-6
Abstrakt: We studied monoamine oxidase activity (MAO) in platelets of patients in the acute period of ischemic stroke. Neurological deficit was evaluated by the data of clinical examinations and scales. In 80% patients MAO activity was considerably increased on 3-5 day after stroke. We found a correlation between increased MAO activity on 3-5 day after ischemic stroke and regression of neurological deficit on day 21 after ischemic stroke. The increase in MAO activity during the acute period of ischemic stroke is presumably a compensatory response aimed at stabilization of tissue homeostasis.
Databáze: MEDLINE
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