| Autor: |
Fomenko LA; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushino, Russia., Lomaeva MG, Bezlepkin VG |
| Jazyk: |
English; Russian |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Feb; Vol. 152 (4), pp. 431-4. |
| DOI: |
10.1007/s10517-012-1546-6 |
| Abstrakt: |
Sibs groups of F1-offspring born by non-irradiated mice and by female mice exposed to X-ray radiation in preconceptive period (50-200 cGy) were compared. Arbitrary primed PCR revealed significantly increased polymorphism of simple DNA repeats in somatic tissues of the offspring from female mice irradiated in a dose of 200 cGy. The increase in DNA polymorphism in postmitotic brain tissues and in peripheral blood was more pronounced than in proliferating spleen tissues and in the epithelium of tail tip. In the tissues of female offspring from irradiated mothers, higher increase in DNA polymorphism was observed in comparison with the tissues of male offspring from the same mothers. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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