Efficiency of structurally different antioxidants in combined myocardial damage in mice.

Autor: Zamotaeva MN; N. P. Ogarev Mordovian State University, Saransk, Russia. zamy03@mail.ru, Inchina VI, Chairkin IN
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Jan; Vol. 152 (3), pp. 318-20.
DOI: 10.1007/s10517-012-1517-y
Abstrakt: Cardioprotective effects of derivatives of 3-hydroxypyridine, benzimidazole, and a peptide substance were studied on the model of combined damage to the myocardium (catecholamines and physical exercises) in mice. The most pronounced antioxidant and cardioprotective effects were produced by 3-hydroxypyridine acetylcysteinate (50 mg/kg), benzimidazole derivative Be-2m (50 mg/kg), and peptide substance γ-glutamyl histamine (1 mg/kg).
Databáze: MEDLINE