Menopausal status and adjuvant hormonal therapy for breast cancer patients: a practical guideline.

Autor: De Vos FY; Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. f.devos@umcutrecht.nl, van Laarhoven HW, Laven JS, Themmen AP, Beex LV, Sweep CG, Seynaeve C, Jager A
Jazyk: angličtina
Zdroj: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2012 Nov; Vol. 84 (2), pp. 252-60. Date of Electronic Publication: 2012 Jul 12.
DOI: 10.1016/j.critrevonc.2012.06.005
Abstrakt: Breast cancer is the most common malignancy amongst women in the developed world. For patients with hormone-sensitive breast cancer eligible for adjuvant hormonal therapy, it is important to know if the ovaries are (still) functional or not. Indeed, the choice for a specific adjuvant hormonal treatment depends on the menopausal status of an individual woman. The currently available measures to determine the menopausal status are conflicting. Until better measures become available, we propose a practical guideline enabling an optimal choice of adjuvant hormonal therapy for women with a hormone receptor positive breast cancer taking into account uncertainties about their menopausal status.
(Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
Databáze: MEDLINE
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