| Autor: |
Levashov PA, Ovchinnikova ED, Afanas'eva MI, Frid DA, Al'muko AA, Bespalova ZhD, Adamova IIu, Afanas'eva OI, Pokrovskiĭ SN |
| Jazyk: |
ruština |
| Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 2012 Jan-Feb; Vol. 38 (1), pp. 58-63. |
| DOI: |
10.1134/s1068162012010141 |
| Abstrakt: |
New chromatographic material based on tryptophil-threonil-tirosine was prepared. This sorbent effectively binds human, sheep, goat and cow immunoglobulins G. New sorbent shows high selectivity for removing immunoglobulins from blood plasma. Effective sorption capacity is 15-25 mg of immunoglobulin G per ml of matrix. Optimal method of covalent attachment ligand to polysaccharide matrix allows achieving high stability of the sorbents in terms of use and storage. This sorbent can be used in medicine and biotechnology. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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