| Autor: |
Victorin LH; Department of Pediatrics, University of Kuwait., Deverajan LV, Curstedt T, Robertson B |
| Jazyk: |
angličtina |
| Zdroj: |
Biology of the neonate [Biol Neonate] 1990; Vol. 58 (3), pp. 121-6. |
| DOI: |
10.1159/000243250 |
| Abstrakt: |
In a neonatal unit which, at that time, had no facilities for artificial ventilation, 14 newborn infants with birth weight greater than or equal to 1,500 g fulfilling the diagnostic criteria for severe hyaline membrane disease (HMD) were treated by tracheal instillation of bovine surfactant (200 mg/kg). Twelve of these babies showed increased transcutaneous PO2/FiO2 ratio within 2 min, the average therapeutic response being sustained for at least 72 h. One of the two babies who did not respond to treatment was later diagnosed as a case of group B streptococcal pneumonia. One baby with favorable initial response died from sepsis at the age of 7 days; the other patients survived without sequelae. We conclude that treatment with exogenous surfactant might be considered as an alternative to ventilator treatment in babies with severe HMD. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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