An improved method for the determination of acetaldehyde in human blood with minimal ethanol interference.
Autor: | Stowell AR |
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Jazyk: | angličtina |
Zdroj: | Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 1979 Nov 02; Vol. 98 (3), pp. 201-5. |
DOI: | 10.1016/0009-8981(79)90146-3 |
Abstrakt: | A sensitive method for the determination of acetaldehyde in human blood is described which involves the derivatization of acetaldehyde with semicarbazide followed by head-space gas chromatographic analysis of acetaldehyde in plasma samples after acid hydrolysis of the semicarbazone derivative. Quantitative recovery of acetaldehyde from human blood was achieved and interference from ethanol, a major problem associated with earlier methods, was negligible. |
Databáze: | MEDLINE |
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