An improved method for the determination of acetaldehyde in human blood with minimal ethanol interference.

Autor: Stowell AR
Jazyk: angličtina
Zdroj: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 1979 Nov 02; Vol. 98 (3), pp. 201-5.
DOI: 10.1016/0009-8981(79)90146-3
Abstrakt: A sensitive method for the determination of acetaldehyde in human blood is described which involves the derivatization of acetaldehyde with semicarbazide followed by head-space gas chromatographic analysis of acetaldehyde in plasma samples after acid hydrolysis of the semicarbazone derivative. Quantitative recovery of acetaldehyde from human blood was achieved and interference from ethanol, a major problem associated with earlier methods, was negligible.
Databáze: MEDLINE