| Autor: |
Gribovsakaia OV, Shutova IV, Tsyganova OV, Martinovich VP, Golubovich VP |
| Jazyk: |
ruština |
| Zdroj: |
Biomeditsinskaia khimiia [Biomed Khim] 2012 Mar-Apr; Vol. 58 (2), pp. 211-9. |
| DOI: |
10.18097/pbmc20125802211 |
| Abstrakt: |
New bioaffine sorbents containing bioselective ligand, synthetic analog of the human thyroperoxidase antigenic determinant--tetrapeptide H-Glu-Gln-betaAla-Lys-OMe, immobilized on two polymeric matrixes--a polyacrylamide gel and CNBr-activated sepharose 4B were synthesized. The offered immunosorbents were shown have high selectivity in relation to autoantibodies against thyroperoxidase and can find an application for medicine and experimental biochemistry for selective elimination of autoantibodies from serum or plasma of the patients suffering from autoimmune thyroid diseases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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