Hospitalization due to human parainfluenza virus-associated lower respiratory tract illness in rural Thailand.

Autor: Morgan OW; Division of Preparedness and Emerging Infections, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., Chittaganpitch M, Clague B, Chantra S, Sanasuttipun W, Prapasiri P, Naorat S, Laosirithavorn Y, Peret TC, Erdman DD, Baggett HC, Olsen SJ, Fry AM
Jazyk: angličtina
Zdroj: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2013 May; Vol. 7 (3), pp. 280-5. Date of Electronic Publication: 2012 Jun 21.
DOI: 10.1111/j.1750-2659.2012.00393.x
Abstrakt: Background: Human parainfluenza viruses (HPIVs) are an important cause of acute respiratory illness in young children but little is known about their epidemiology in the tropics.
Methods: From 2003-2007, we conducted surveillance for hospitalized respiratory illness in rural Thailand. We performed reverse-transcriptase polymerase chain reaction on nasopharyngeal specimens and enzyme immunoassay on paired sera.
Results: Of 10,097 patients enrolled, 573 (5%) of all ages and 370 (9%) of children <5 years of age had evidence of HPIV infection (HPIV1=189, HPIV2=54, HPIV3=305, untyped=27). Average adjusted annual incidence of HPIV-associated hospitalized respiratory illness was greatest in children aged <1 year (485 per 100,000 person years).
Conclusions: In Thailand, HPIV caused substantial illnesses requiring hospitalization in young children.
(Published 2012. This article is a US Government work and is in the public domain in the USA.)
Databáze: MEDLINE
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