[The influence of ezetimibe and simvaststin on platelet aggregation and protein c system in patients with coronary heart disease and hypercholesterolemia].

Autor: Vashchenko VI, Kozobova AI, Filippov AE, Chechetkin AV, Popova NN, Vil'ianinov VN, Vashchenko TN
Jazyk: ruština
Zdroj: Klinicheskaia meditsina [Klin Med (Mosk)] 2012; Vol. 90 (3), pp. 66-8.
Abstrakt: Therapy with ezetimib (10 mg daily for 2 weeks) caused a 24% reduction of plasma LDL cholesterol level (p < 0.05) and maximum ADP and collagen-induced platelet aggregation from 76.2 +/- 1.54 to 65.3 +/- 3.38% and from 71.5 +/- 3.98 to 53.6 +/- 5.24% (p < 0.05) respectively. Combination of ezetimibe and simvaststin did not produce an additional decrease in platelet aggregation.
Databáze: MEDLINE