Exploratory planning and implementation of a pilot pharmacogenetic program in a community pharmacy.
| Autor: | O'Connor SK; Division of Pharmacy Practice & Experiential Education CB #7574, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7574, USA., Ferreri SP, Michaels NM, Greco AJ, Viera AJ, Faruki H, McLeod HL, Roederer MW |
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| Jazyk: | angličtina |
| Zdroj: | Pharmacogenomics [Pharmacogenomics] 2012 Jun; Vol. 13 (8), pp. 955-62. |
| DOI: | 10.2217/pgs.12.67 |
| Abstrakt: | Aim: To describe the exploratory planning and implementation of a pilot pharmacogenetic program in a community pharmacy. An institutional review board-approved protocol for a clopidogrel pharmacogenetic program in a community pharmacy was developed to address feasibility and evaluate the pilot program. Study Concept: Subjects taking clopidogrel are asked to participate at the point of medication dispensing. A pharmacist schedules an appointment with subjects to discuss the study and collects a buccal swab sample for CYP2C19 testing. When the results are available, the pharmacist consults with the subject's prescriber regarding test result interpretation and associated recommendations, and schedules a second appointment with the participant to discuss results and review any physician-approved therapeutic changes. The intervention-associated consultation is then billed to the subject's insurance. Results: Subject enrollment has begun. Conclusion: Community pharmacists may be valuable partners in pharmacogenetics. |
| Databáze: | MEDLINE |
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