Prevalence of undiagnosed HIV infection in patients with ocular surface squamous neoplasia in a tertiary center in Karnataka, South India.

Autor:	Pradeep TG; Minto Ophthalmic Hospital, Cornea Department, Bangalore Medical College and Research Institute, Bangalore, India. thanugopal@yahoo.co.in, Gangasagara SB, Subbaramaiah GB, Suresh MB, Gangashettappa N, Durgappa R
Jazyk:	angličtina
Zdroj:	Cornea [Cornea] 2012 Nov; Vol. 31 (11), pp. 1282-4.
DOI:	10.1097/ICO.0b013e3182479aed
Abstrakt:	Purpose: To evaluate the prevalence of undiagnosed and asymptomatic human immunodeficiency virus (HIV) infection in patients with ocular surface squamous neoplasia (OSSN) in a referral hospital in Karnataka, South India. Methods: A consecutive series of patients presenting with OSSN were evaluated in an academic center during January 2009 to June 2010. A detailed history was obtained and physical examination in 25 consecutive patients with OSSN was performed. Twenty-three patients (88%) agreed to undergo serological HIV testing. Of these, 2 were excluded from the current study because they had xeroderma pigmentosa, a known predisposing factor for OSSN. Results: Of the 21 patients, 6 (29%) patients were HIV positive. None of the patients had previous HIV testing. The median age of presentation among HIV-positive patients was 36 years, whereas it was 54 years among HIV-negative patients. The mean CD4 count in HIV-positive patients was 133 cells per mm, and all patients were started on antiretroviral treatment. Conclusions: The conjunctival tumor may be the primary and the only apparent manifestation of HIV in patients presenting with OSSN, and the ophthalmologist needs to be aware of this association.
Databáze:	MEDLINE
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