Aortic flow propagation velocity as an early predictor of high coronary risk in hypertensive patients.
| Autor: | Yıldırım M; Department of Cardiology, Gulhane Military Medical School, Etlik, Ankara, Turkey., Yiginer O, Uzun M, Yilmaz Cingozbay B, Sag C, Kutsi Kabul H, Uz O, Isilak Z, Kardesoglu E, Sitki Cebeci B |
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| Jazyk: | angličtina |
| Zdroj: | Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina [Med Glas (Zenica)] 2012 Feb; Vol. 9 (1), pp. 42-8. |
| Abstrakt: | Aim: To assess the value of aortic flow propagation velocity (Vp) in detecting hypertensive patients with coronary risk. Methods: The study included 120 patients with hypertension. According to the 10-year risk of coronary heart disease the patients were categorized in the three groups: 10-year risk < 10% (I),10 - year risk=%10 - 20 (II), and 10-year risk > 20% (III). The aortic flow propagation velocity (Vp) was measured from descending aorta with color M-mode echoardiography. The slope of the first aliasing contour was accepted as Vp. It was compared with Framingham coronary risk score, carotid intima media thickness and high sensitive C-reactive protein. Twelve patients were excluded from the study due to poor acoustic window. Results: The Vp was significantly lower (p<0.001), carotid intima media thickness and high sensitive C-reactive protein was significantly higher in group III (p=0.002 and p=0.014). The area under ROC curve of Vp, carotid intima media thickness and high sensitive C-reactive protein were 0.890, 0,700 and 0.664, respectively. There was a significant inverse relation between Vp and carotid intima media thickness (r=-0.37; p<0.001). Conclusions: The aortic flow propagation velocity is a simple, feasible and reproducible marker of atherosoclerosis with an acceptable sensitivity and specificity. There is a need for longitudinal prospective studies to use it routinely. |
| Databáze: | MEDLINE |
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