Analytical methods for characterizing magnetic resonance probes.
| Autor: | Manus LM; Department of Chemistry, Molecular Biosciences, Neurobiology, Biomedical Engineering, and Radiology, Northwestern University, Evanston, Illinois 60208-3113, USA., Strauch RC, Hung AH, Eckermann AL, Meade TJ |
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| Jazyk: | angličtina |
| Zdroj: | Analytical chemistry [Anal Chem] 2012 Aug 07; Vol. 84 (15), pp. 6278-87. Date of Electronic Publication: 2012 May 23. |
| DOI: | 10.1021/ac300527z |
| Abstrakt: | The efficiency of Gd(III) contrast agents in magnetic resonance image enhancement is governed by a set of tunable structural parameters. Understanding and measuring these parameters requires specific analytical techniques. This Feature describes strategies to optimize each of the critical Gd(III) relaxation parameters for molecular imaging applications and the methods employed for their evaluation. |
| Databáze: | MEDLINE |
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