CT findings and long-term mortality after pulmonary embolism.
| Autor: | Morris MF; Department of Radiology, Mayo Clinic and Mayo Foundation, Scottsdale, AZ, USA., Gardner BA, Gotway MB, Thomsen KM, Harmsen WS, Araoz PA |
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| Jazyk: | angličtina |
| Zdroj: | AJR. American journal of roentgenology [AJR Am J Roentgenol] 2012 Jun; Vol. 198 (6), pp. 1346-52. |
| DOI: | 10.2214/AJR.11.6801 |
| Abstrakt: | Objective: The utility of CT findings in predicting long-term mortality in patients with acute pulmonary embolism (PE) is unknown. The purpose of this study is to retrospectively determine whether three CT findings--increased embolic burden, interventricular septal bowing toward the left ventricle, and right ventricle-to-left ventricle (RV/LV) diameter ratio greater than 1--are independent predictors of long-term all-cause mortality after acute PE. Materials and Methods: A total of 1105 patients (47% female; mean age, 63 ± 16 years) with CT scans positive for PE from January 1, 1997, to December 31, 2002, were included. Scans were independently interpreted by two observers, with a third independent observer reviewing discrepant cases. CT findings and clinical information were compared with all-cause mortality using univariate and multivariate logistic regression analyses. Results: The median duration of survival was 6.2 years following acute PE, with estimated 10-year survival of 37.4%. CT-derived embolic burden was associated with a very small decrease in long-term all-cause mortality in both univariate (hazard ratio [HR], 0.97; p < 0.001) and multivariate (HR, 0.97; p < 0.001) analyses. Interventricular septal bowing and RV/LV diameter ratio were not significantly associated with long-term all-cause mortality. Conclusion: CT findings are not predictive of decreased long-term survival after acute PE. |
| Databáze: | MEDLINE |
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