| Autor: |
Haimanot RT; Faculty of Medicine, Addis Ababa University, Ethiopia., Kidane Y, Wuhib E, Kalissa A, Alemu T, Zein ZA, Spencer PS |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of epidemiology [Int J Epidemiol] 1990 Sep; Vol. 19 (3), pp. 664-72. |
| DOI: |
10.1093/ije/19.3.664 |
| Abstrakt: |
Lathyrism is a disorder of the central motor system, induced by heavy consumption of the grass-pea, Lathyrus sativus an environmentally tolerant legume containing the neurotoxic excitatory amino acid beta-N-oxalylamino-L-alanine (BOAA). A complete door-to-door resurvey of the Dembia and Fogera regions of northwestern Ethiopia, areas endemic for lathyrism, revealed an estimated mean disease prevalence of 0.6%-2.9%. Most patients developed the disease in the epidemic of 1976/77, although new cases appear to have occurred with an estimated mean annual incidence of 1.7:10,000. Production and consumption of grass-pea is increasing in Ethiopia, making attempts to develop low-BOAA strains to prevent lathyrism increasingly important. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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